The chances of getting pregnant with an immature follicle are relatively small, and it is recommended that treatment be carried out under the guidance of a doctor before preparing for pregnancy. The development of follicles is a physiological process. Generally, follicles will reach a state of dominance in the middle of menstruation, and will rupture and discharge an egg at about 14 days before the next menstruation. Conception occurs when the egg combines with the sperm. When the follicles are immature, ovulation may not occur or the eggs discharged may be of poor quality, and the probability of pregnancy is generally low. Causes of follicular immaturity may include congenital ovarian hypoplasia, polycystic ovary syndrome, premature ovarian failure, ovarian cysts and other ovarian pathologies, and may also be related to systemic diseases such as severe malnutrition and hyperthyroidism. It is recommended that patients under the guidance of the doctor to carry out the appropriate examination to clarify the cause, and then standardized treatment.