There are five main possibilities for chest pain on pressure: 1. cystic hyperplasia of the breast, which occurs in women aged 30-50, with clinical manifestations of breast swelling and pain, and the swelling is mostly aggravated before menstruation and relieved after menstruation, and can be accompanied by increased pain on pressure. 2. pleurisy, mostly secondary to lung infection, as a limited pressure pain, not accompanied by radiating pain from other parts. 3. acute pancreatitis or cholecystitis, manifesting as pain in the middle and upper abdomen, and Acute mastitis, which occurs in lactating women, is a painful swelling of the whole breast with fluctuating lump formation. 5. chest wall injury, when the chest wall is struck by external forces, can cause an acute inflammatory reaction in the local tissue, manifesting as redness and swelling with painful discomfort. Therefore, when the chest appears to press the pain, should promptly to the regular hospital to seek medical attention, clear lesion site, and timely treatment.