Polio salk is an injectable inactivated vaccine and sabin is an oral attenuated vaccine, and there are some differences in how they are used and what they are indicated for. Both polio vaccines are used to prevent poliomyelitis. The salk vaccine is a vaccine made by inactivating the poliovirus, which is relatively safe and can be used in children with immunodeficiency or AIDS. However, the duration of antibody production after injection is relatively short. The sabin vaccine is a vaccine made by attenuating the poliovirus and is administered orally in the form of “sugar pills” to stimulate the body to develop immunity. Because the virus is still active, it is not recommended for use in children with AIDS and immunodeficiencies. Compared to the SALK vaccine, its immune effect lasts for a relatively long time. It is recommended to consult a medical professional before vaccination to choose the type of vaccine to be used.