Acute osteomyelitis is indeed more serious, mainly reflected in the systemic manifestations and local manifestations. The systemic manifestations are mainly acute osteomyelitis with a relatively rapid onset, and at the beginning, there will be typical chills, high fever, vomiting, and septicemia-like episodes. Before the onset of acute osteomyelitis, there will be certain precursor symptoms, such as generalized lethargy, generalized aches and pains, lack of appetite, chills, and chills, which can be accompanied with chills, and most often present as a spiked high fever with a temperature of more than 39 degrees Celsius, accompanied by a rapid pulse rate, a dry mouth, and a lack of appetite, with headache, vomiting and other symptoms of meningeal irritation, patient agitation and restlessness. The symptoms of meningeal irritation, such as headache and vomiting, are accompanied by agitation, delirium and coma in severe cases, as well as infectious shock. Patients can be dehydrated and acidotic, and neonates and lactating infants express themselves poorly, show easy excitement, do not eat milk, cry during diaper changes, and often consult pediatrics because of high fever or vomiting, thinking it is a respiratory or intestinal disease. Local manifestations will also be more serious, acute osteomyelitis early will have localized, myelitis onset site will have severe pain, especially the throbbing pain was throbbing pain, is due to the bacteria in the bone marrow in the bone dry parts of the bone marrow reproduction, there will be severe congestion of the local area because of inflammation and inflammation exudate, caused by intraosseous pressure within the bone, intraosseous pressure is particularly high, there is severe pain, muscle spasm, limb protection. Not daring to move, the patient often puts the limb in a protective position in order to alleviate the pain, usually by refusing to move the affected limb both actively and passively.