Upper abdominal pain in early pregnancy may be due to early pregnancy reaction, but also does not exclude pathological causes such as combined acute cholecystitis, acute fatty liver and so on. 1. Early pregnancy reaction: after pregnancy, the hormone level of the body changes, pregnant women will have early pregnancy reaction such as nausea, vomiting, etc., if a long time can not be relieved, there may be indigestion of the stomach, pregnant women can feel the pain in the epigastric region, soreness and bloating. 2. Acute cholecystitis: If the pregnant woman has acute cholecystitis in early pregnancy, she may have colic pain in the right upper abdomen after consuming greasy food, and it may also radiate to the right shoulder. 3. Acute Fatty Liver Disease: If a pregnant woman suffers from acute fatty liver disease, she may have pain in the upper abdomen, which is usually accompanied by nausea, vomiting and other gastrointestinal symptoms. If a pregnant woman has epigastric pain in early pregnancy, it is recommended to consult a doctor in time, under the guidance of the doctor, complete the relevant examinations, identify the cause of the disease, and treat the cause of the disease.