The upper part of the stomach at the fossa of the heart to block and hold difficult may be digestive system diseases, cardiovascular disease, neurosis and other diseases caused by, according to the cause of the disease to take general treatment, drug therapy and intervention and other treatments. 1. Digestive system diseases: for example, gastritis, gastric ulcer. Proton pump inhibitors, such as lansoprazole, omeprazole or H2 receptor antagonists, such as cimetidine, ranitidine, etc., are often chosen. Digestive aids are given, such as vincristine and multienzymes tablets. For patients with bloating, relief can be achieved with a combination of drugs that enhance gastrointestinal motility, such as domperidone and mosapride. If there is Helicobacter pylori infection, it is also necessary to give amoxicillin, clarithromycin combined with omeprazole, bismuth pectin and other sterilization. 2. cardiovascular disease: for example, angina pectoris, acute myocardial infarction, etc., which can have a sudden onset, if available, should be timely sublingual nitroglycerin dilation of the coronary arteries, and timely access to medical care, through electrocardiography and other tests to clarify the condition, for acute myocardial infarction, should be immediately oral aspirin, clopidogrel and other medications, and thrombolytic therapy, interventional therapy, etc. to relieve the symptoms in the time window. 3. Neurosis: you can choose to use drugs that regulate the function of autonomic nerves, such as ghrelin, vitamin B, methylcobalamin and so on. The upper part of the stomach at the heart fossa blocked hard to hold the cause is more, should promptly consult a doctor, under the guidance of the doctor to improve the examination, and targeted treatment, the drug should be in accordance with the doctor’s prescription treatment.