There is no fastest way to treat HFMD, it can be treated by general treatment, medication, blood purification and so on. 1. General treatment: It is recommended that patients wear wide and soft clothes, and pay attention to keep the mouth clean, rinse the mouth after eating, and wash the hands in time after defecation, which can prevent the occurrence of secondary bacterial infections. For patients with fever can be cold compresses, warm water baths and other physical cooling. 2. Drug therapy: there is still a lack of specific and efficient antiviral drugs, but in the early stage, drugs such as ribavirin can be used as appropriate, but we need to pay attention to its adverse effects and biological toxicity. For people with headache, fever, generalized muscle pain and other symptoms, acetaminophen, ibuprofen and other drugs can be used to relieve the symptoms under the guidance of the doctor. 3. Blood purification: It is suitable for those who are critically ill with HFMD, and helps to reduce inflammation, assist the body to maintain fluid balance, and replace some of the functions of the kidneys. If you are found to have hand, foot and mouth disease, you need to go to a regular hospital, under the guidance of the doctor for medication and treatment, so as not to delay the condition.