Heartburn in the morning may be caused by cardiogenic diseases, autonomic disorders, digestive diseases, patients should consult a doctor in time to clarify the cause of the disease. 1. Cardiogenic diseases: common cardiogenic diseases that can cause vague pain in the heart in the morning are unstable angina pectoris, hypertrophic obstructive cardiomyopathy and so on. (1) unstable angina: a type of acute coronary syndrome, mostly due to atherosclerotic plaque rupture leading to thrombosis in the coronary artery, patients will have a vague pain in the heart in the morning, mostly lasting more than 20 minutes, accompanied by sweating, nausea, skin pallor and other symptoms, you can use nitroglycerin, clopidogrel and other drugs for treatment. (2) Hypertrophic obstructive cardiomyopathy: If there is vague pain in the heart when getting up in the morning, accompanied by weakness, dizziness, fainting and other symptoms, it should be considered to be caused by hypertrophic obstructive cardiomyopathy, and it can be treated with metoprolol and other drugs. 2. Autonomic disorders: if the patient is in long-term mental stress, long-term late-night after the emergence of vague pain in the morning heart, should be considered to be caused by autonomic disorders, such people should pay attention to rest, do appropriate physical exercise, if necessary, can be treated with ghrelin. 3. Digestive system diseases: the digestive system diseases that can cause vague pain in the heart in the morning are duodenal ulcer, gastroesophageal reflux disease, etc. Such people often have acid reflux, nausea and other symptoms, and can be treated with drugs such as omeprazole. All of the above drugs should be used under the guidance of a doctor, and follow the doctor’s instructions for standardized treatment.