Cold and painful ankles are commonly caused by the following reasons: First, insufficient blood supply to the arteries of the lower extremities: If the lumen within the arteries of the lower extremities becomes thin, it will lead to insufficient vascular supply to the lower extremities, and the patient will get cold around the ankle joints with clinical symptoms of pain. Stenotic lesions in the blood vessels will be found through ultrasound examination. Secondly, rheumatic joint disease: there are clinical manifestations of cold and painful ankle joints, accompanied by joint swelling and restricted movement, usually with bilateral symmetrical onset, and the onset is relatively rapid. Most patients have a history of upper respiratory tract infection. Through early diagnosis and early treatment, the clinical symptoms of cold and painful ankles can be relieved rapidly.