Tuberculosis is most contagious during the exclusion phase. Clinically, cavitary tuberculosis, infiltrative tuberculosis, is the most contagious, while tuberculous pleurisy is not contagious. If the patient is cavitary tuberculosis, appropriate isolation should be performed with children and the elderly, and special isolation should be performed with patients with reduced immune function, such as patients with diabetes, rheumatic immune system diseases, and long-term oral glucocorticoid administration, otherwise cross-infection can easily occur through droplet transmission. Patients diagnosed with tuberculosis should be actively treated to reduce bacterial excretion, and the infectiousness will be significantly reduced, and the anti-tuberculosis drugs to be used include isoniazid, rifampin, pyrazinamide, streptomycin, etc.