If you feel your heart is thumping when you lie down, you need to consult the cardiology department for cardiac ultrasound, electrocardiogram, dynamic electrocardiogram, etc., monitor your blood pressure, and give treatment accordingly after clarifying your condition. If the cardiac ultrasound examination, the patient’s myocardial structural function or valve abnormalities, may lead to the patient consciously lying down on the heart thumping, such as congenital mitral valve malformation and other conditions, myocardial function is gradually impaired, there may be such a manifestation. Prompt formal and systematic treatment of valve disease and myocardial disease is needed. If the heart rhythm is checked, electrocardiogram and 24-hour dynamic electrocardiogram are performed. If there are arrhythmias, such as premature beats, paroxysmal atrial fibrillation, etc., which may lead to the patient’s self-consciousness of the heart thumping when he/she is lying down, it is necessary to give different medications for different arrhythmias, such as the application of mesirelone, propafenone, and amiodarone. If the patient’s examination of cardiac ultrasound, 24-hour dynamic electrocardiogram results are normal, it is recommended that the patient monitor blood pressure, if the blood pressure fluctuation may also cause this symptom, need to be formalized in the Department of Cardiology to adjust antihypertensive treatment. If the examination results are normal and the blood pressure is normal, the patient can be instructed to adjust the mood, observe whether it may be autonomic dysfunction, consult the Department of Neurology, and appropriately give the regulation of neurological treatment.