Metoprolol extended-release tablets can be taken orally under the supervision of a physician once a day, and the specific dosage of the drug needs to be based on the severity of the disease. 1. Metoprolol is a selective β1-blocker, which can reduce heart rate and blood pressure by inhibiting myocardial contractility and cardiac electrical signaling, and is mainly used in the treatment of hypertension, angina pectoris, myocardial infarction and cardiac arrhythmias. 2. Common adverse effects of Metoprolol include fatigue, headache, dizziness, bradycardia, etc. It may also lead to gastrointestinal reactions such as abdominal pain, nausea, vomiting and diarrhea. 3. It should be noted that, allergic to the drug, patients with cardiogenic shock, patients with sick sinus node syndrome, patients with a high degree of atrioventricular block is contraindicated, pregnant women and lactating women need to be used with caution. 4. For metoprolol extended-release tablets, because of its slow release in the body of the characteristics of the drug, can be done once a day to take the drug, the patient compliance is higher; the dose of the drug can not meet the requirements, you can break the tablets to take, but can not chew, which will lead to the destruction of the drug’s slow-release structure. In the use of medication, must follow the doctor’s instructions, rational application of drugs, do not use drugs, to avoid causing serious adverse reactions.