There are many checkup items for plague, including routine blood test, fecal routine test, coagulation function, cerebrospinal fluid and other routine checkups, as well as smear test, bacterial culture, serological examination and so on. 1. Routine examination: for example, routine blood examination, routine fecal examination, from which white blood cells, platelets and hemoglobin can be analyzed whether they are within the normal range; after that, coagulation function screening can be done to know the prothrombin time and whether there is any coagulation abnormality, etc. Cerebrospinal fluid screening is needed to find out whether there is any increase in pressure if necessary. 2. Smear examination: mainly smear examination with blood, urine, feces and cerebrospinal fluid to exclude Pseudomonas aeruginosa infection. 3. Bacterial culture: If the patient has enlarged lymph nodes, its fluid or purulent secretion can be drawn for diagnostic analysis. 4. Serological examination: it mainly includes antigen detection and antibody detection to analyze whether there is plague infection according to the values of antigen and antibody. In addition, molecular biology testing can also be used to determine whether the infection of plague, the specific should be carried out under the guidance of a professional physician, once diagnosed, it should be treated in a timely manner.