Segmental motion abnormalities of the left ventricular wall are usually detected on cardiac ultrasound and are mainly characterized by decreased, uncoordinated, or even absent motion of the ventricular wall in certain parts of the left ventricular wall. Segmental motion abnormalities of the left ventricular wall are usually seen in myocardial ischemia and myocardial infarction, because the coronary blood supply is distinctly segmental in nature, and is closely related to the regional phases of cardiac motion. Segmental motion abnormalities of the left ventricular wall are also seen in hypertrophic cardiomyopathy, pulmonary heart disease, myocarditis, bundle branch block, cardiac tamponade, and pulmonary embolism. If a patient is found to have abnormal segmental motion of the left ventricular wall during cardiac ultrasound, it is recommended that the cause be determined and treated as soon as possible.