Insomnia is a common and stubborn clinical condition, and many patients have been suffering from it for more than 10 years. According to Prof. Zhou Pingan, although this kind of insomnia has the clinical manifestation of irritability and agitation, it is mostly accompanied by tiredness and weakness, with a light tongue and thin waiting pulse, which is actually a sign of deficiency fire and belongs to the deficiency evidence. It can be caused by blood deficiency, qi deficiency or yin deficiency, resulting in loss of nourishment of the heart and mind and disturbance of the phase fire, but it is always a deficiency of the root and the symptoms; the main pathogenesis is deficiency of the heart and spleen in both qi and blood, non-interaction of the heart and kidney, deficiency of blood in the heart and liver or yin deficiency for fire. As the Jing Yue Quan Shu discusses: “Although the disease of sleeplessness has different, but only know the two characters of evil and positive is complete. The sleep is not sleepy because it is disturbed by the evil and the lack of Ying Qi. Those who have evil are more real, and those who do not have evil are deficient. Without evil and sleeplessness, must be insufficient Ying Qi, Ying main blood, blood deficiency is not to nourish the heart, the heart deficiency is not guarded by the gods.” Zhang Zhongjing’s sour date soup is often used to treat this type of insomnia with the addition and subtraction of the main formula. In the book “Jin Kui Essentials? Blood paralysis, deficiency labor pulse evidence and treatment, the sixth says: “deficiency labor, deficiency labor and sleeplessness, sour date and nut soup is the mainstay. The main remedy in this formula is sour jujube nut to nourish the heart and tranquilize the mind; Fu Ling strengthens the spleen and permeates dampness, targeting phlegm, dampness and turbidity due to spleen deficiency, so that the spleen can be healthy and the mind can be at ease: Zhi Mu can clear the heart and remove annoyance, and nourish Yin, so that Yin is sufficient to contain the deficiency fire and not disturb the mind, and can drain the phase fire and calm the ruler fire, so that the mind can be at ease and sleep; Chuan Xiong nourishes the Blood and invigorates the Blood, unblocking the Blood vessels. Chuanxiong nourishes Blood, invigorates Blood, and unblocks Blood vessels to relieve Blood flow and stagnation caused by Blood deficiency. The combined formula nourishes the heart, spleen, qi and blood, resolves phlegm, clears deficiency fire, and clears the blood vessels. In clinical application, Wu Wei Zi is mostly used in combination with licorice to transform yin with acidity and sweetness, so that yang crosses over yin and yin automatically becomes quiet, achieving the purpose of regulating yin and yang; adding Jiaotai Wan to induce fire to return to its source, so that yin and yang can be harmonized, and water and fire can be harmonized; adding Sheng Long Bone, Sheng Oyster and Mother of Pearl to calm the mind and subdue yang and astringent yin in cases of palpitation and panic; adding Dan Shen, Red Peony, Chuan Xiong and Yu Jin in cases of dullness and palpitation; adding Bai Shao, Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Rehmanniae Sinensis, Radix Rehmanniae Sinensis, Radix Rehmanniae Sinensis and Radix Rehmanniae Sinensis in cases of obvious deficiency heat. If the deficiency of heat is obvious, add white peony, angelica, raw earth, chicken blood vine, jujube or Agaricus to nourish the blood; if the deficiency of yin is obvious, add lily, chasteberry, dry lotus grass or asparagus to nourish the yin of the liver and kidney; if the yang deficiency or long term treatment is ineffective, add cinnamon stick, deer horn gum, Xian Ling spleen, Xian Mao; also often use 30 grams of nightshade vine to nourish the blood, pass through the channels and calm the mind. It is sweet and flat in nature, enters the heart and liver meridians, nourishes yin and blood, glorifies the ligaments, and harmonizes yin and yang, and can tranquilize the heart and kidney. Example: The patient, female, 70 years old, was first diagnosed on February 5, 2004. She has been suffering from insomnia for many years and sleeps a lot at night. Three months ago, her insomnia was aggravated by mental stimulation, and she has difficulty falling asleep, waking up easily after light sleep, palpitations, restlessness, heat in the hands and feet, dullness, red tongue with white fur and sunken pulse. The diagnosis is that the deficiency of heart blood, deficiency of fire and loss of nourishment of the heart and mind are the evidence of deficiency of the root and the symptoms. The treatment is to nourish Yin and Blood, tonify the heart and calm the mind. Herbs: 30g of sour date, 6g of Chuanxiong, 10g of Zhi Mu, 15g of Fu Ling, 15g of Bai Shao, 15g of Dan Shen, 20g of Ligustrum, 20g of Wu Wei Zi, 15g of Lily, 10g of Angelica, 30g of Nightshade, 30g of Calamus, 30g of Raw Dragon Bone, 30g of Raw Oyster, 0.6g of Pearl Powder, 7 doses, one dose daily, decoction with water, once in the morning and once in the evening. 2004 The second consultation was held on February 12, 2004. After taking the medicine, the patient’s sleep improved and he could fall asleep more easily than before, his palpitations were reduced, but he was still anxious and restless. Prescription: 30g of sour date palm, 6g of Chuanxiong, 10g of Zhi Mu, 15g of Fu Ling, 15g of Bai Shao, 15g of Dan Shen, 20g of Ligustrum, 20g of Wu Wei Zi, 15g of Lily, 10g of Angelica, 30g of Nightshade, 30g of Acorus calamus, 10g of Yuan Zhi, 15g of Hopi skin, 0.6g of pearl powder, 7 doses, one dose daily, decoction in water, once in the morning and once in the evening. On February 19, 2009, the third consultation, the patient’s sleep significantly improved, faster sleep, sleep is more solid, sometimes palpitations, can, light red tongue with thin white coating, thin pulse, followed by the above 14 payments to consolidate the effect of treatment.