Although keloids are rarely malignant, they often affect aesthetics and dysfunction. Drug therapy mainly includes the following categories: 1. glucocorticoids such as Quanexed and Depo-Provera, which are more commonly used on a daily basis; 2. drugs containing silicone components: such as silicone gel and silicone cream; 3. some immunosuppressive agents, anti-inflammatory agents, cell-targeting drugs, etc.; 4. emerging drugs, such as botulinum toxin, in the treatment of keloids has been recognized by more experts. The patient with keloid scars should choose which medication to choose, and should go to a regular hospital to be guided by a professional doctor to develop a reasonable treatment plan according to the individual situation.