Ibuprofen 2 hours after the fever has not gone down, after a clear diagnosis can be through physical cooling, medication and other methods to reduce fever. 1. Physical cooling: If the fever does not go down after taking ibuprofen for 2 hours, you can use warm water towel to scrub the armpits, behind the ears, thigh roots, elbow sockets and other parts of the large blood vessels, each time for more than 10 minutes; you can also use antipyretic patches, and at the same time, drink plenty of lukewarm water to promote blood circulation, promote the sweat, and always monitor the changes in body temperature. 2. Medication: If the fever cannot be relieved by the above treatment, you should consult a doctor as soon as possible to find out the cause, and determine whether it is caused by viral or bacterial infection, or by other conditions. If it is caused by a viral infection, use antiviral drugs, such as ribavirin granules, to clear the body of viruses and alleviate the symptoms; if it is caused by a bacterial infection, you need to follow the doctor’s instructions to take cefixime and other drugs for anti-infective treatment to clear the body of bacteria, which will help reduce the fever. There are many other causes of fever, which need to be diagnosed as soon as possible. If the fever does not go down within 2 hours after taking ibuprofen, it is recommended to go to the hospital for a checkup, follow the doctor’s advice and actively cooperate with the treatment after a clear diagnosis. The use of drugs must follow the doctor’s instructions, not blindly use their own medicine, so as not to cause adverse consequences.