Endocrine therapy mainly includes the following methods: 1. Anti-estrogenic drugs: Tamoxifen, for example, inhibits the development of breast cancer by binding to the estrogen receptors in breast cancer cells and blocking the binding of estrogen to the receptors, thus eliminating the stimulation of estrogen on the growth and proliferation of breast cancer cells. It is suitable for the treatment of breast cancer in pre- and post-menopausal women. 2.Aromatase inhibitors: The conversion of androgens to estrogens catalyzed by aromatase in peripheral tissues, such as fat and muscle, is the main pathway of estrogen synthesis in postmenopausal women. The main function of aromatase inhibitors is to inhibit aromatase, prevent the conversion of androgens to estrogens and reduce the level of estrogen in the body, thus reducing the stimulation of estrogen to breast cancer cells. It is suitable for the treatment of postmenopausal hormone-dependent breast cancer. 3.Other: drugs that can regulate the endocrine environment in the body and inhibit the secretion of estrogen by the ovaries, such as luteinizing hormone-releasing hormone analogues, progestins and androgens.