Hashimoto’s disease is an autoimmune disease, in which the autoimmune system causes damage to the thyroid tissue, which usually does not affect life expectancy. The main changes in Hashimoto’s disease are a large infiltration of lymphocytes and fibrous tissue hyperplasia in the thyroid tissue. As the disease progresses, the number of damaged thyroid cells gradually increases, so the thyroid function will appear hypothyroidism phenomenon, can be adjusted to the normal level of hormone levels through hormone replacement therapy, the majority of patients with a better prognosis, will not affect the normal life expectancy. If hypothyroidism occurs and is not treated, heart failure may occur, which can seriously affect normal life expectancy. In the case of severe heart failure, survival time is usually 3-5 years if the patient is not treated. Therefore when Hashimoto’s disease is detected, it is important to go to the endocrinology department of the hospital for a thyroid function test, and the doctor will develop a personalized treatment plan based on the test results. During hormone replacement therapy, ultrasound, as well as thyroid function and thyroid antibodies should be rechecked regularly.