The most common clinical cause of occasional thigh stabbing pain is muscle strain, inflammation of the fascia, or ligament strain in the thigh area due to prolonged standing or strenuous exercise, which results in pain. The main manifestations are localized soreness, swelling, tingling, and occasionally radiating pain, which can be reduced when resting in bed, but may develop when exercising vigorously. In this case, first of all, attention should be paid to rest, local massage or hot compress treatment can be carried out, and non-steroidal anti-inflammatory and analgesic drugs can also be used for symptomatic treatment. It may also be due to lumbar disc herniation, as the herniated disc compresses the nerve, resulting in radiating pain or pins-and-needles pain in the innervated area. In this case, CT or MRI examination of the lumbar spine should be improved to clarify the degree of disc herniation and herniated segments, and then choose the appropriate treatment plan according to the situation.