In most cases, when oral anti-inflammatory drugs are used to treat infectious diseases in male patients, they do not cause changes in the reproductive system, but they should be divided according to the specific time of application and the amount of medication. If anti-inflammatory or antiviral drugs are applied for a long time, it is possible that they may affect the intestinal flora of the body leading to microecological disorders, which in turn lead to disorders of nutrients and metabolic substances of the organism. Impaired utilization of raw materials for sperm production occurs, which indirectly affects the reproductive system. However, for short-term application of drugs, such as checking for urinary tract infections or having symptoms of fever, short-term application of anti-inflammatory drugs does not cause significant disorders. Therefore, anti-inflammatory drugs do not necessarily cause disorders of the reproductive system, unless they are used in large quantities for a long time and for a long period of time to cause indirect reactions.