The best treatment for advanced cholangiocarcinoma is individualized treatment according to the patient’s condition. The overall survival period of advanced cholangiocarcinoma is low, about 6 months, and different treatment methods are chosen according to the patient’s condition or disease. If the jaundice is obvious, ptcd, which is to drain the bile outside the patient’s body through a liver puncture tube, can be used if necessary to improve the jaundice and improve the itching of the patient’s skin and liver function impairment, which can effectively prolong the overall survival time of the patient. If the patient’s nutritional status is poor and diet is low, nutrition is increased if necessary, and enteral nutrition and parenteral nutrition are used to treat the patient.