Biological therapy, as a new type of treatment, is now increasingly used in clinical practice. Generally speaking, biologic therapy is mainly applied to solid tumors clinically its indications mainly include malignant melanoma, bladder cancer, ovarian cancer, prostate cancer, kidney cancer, colon cancer, breast cancer, rectal cancer, lung cancer, cervical cancer, nasopharyngeal cancer, laryngeal cancer, pancreatic cancer, liver cancer, stomach cancer and other solid tumors. In order to prevent recurrence of surgery, it can also be used for the treatment of hematologic diseases such as multiple myeloma, B-lymphoma and leukemia, as well as for further consolidation and enhancement of the above-mentioned tumors, in order to prolong patients’ survival, improve their quality of life and inhibit tumor deterioration.