Swelling of the hands during pregnancy can be seen in physiological causes, but it can also be caused by certain diseases, such as pregnant women with combined liver disease, hypertension during pregnancy and so on. Under physiological circumstances, the continuous growth and development of the fetus in the mother’s body during pregnancy requires a large amount of nutrients from the mother’s body, the pregnant woman’s blood volume will increase, while the increase in the rate of protein is relatively slow, there will be physiological hypoproteinemia, resulting in swollen hands during pregnancy. In addition to the hormones secreted by the placenta can lead to water and sodium retention in the pregnant woman’s body, which can also lead to swollen hands, these conditions lead to swollen hands during pregnancy with a good prognosis. If pregnant women with liver disease, can lead to protein synthesis and utilization of obstacles, may appear edema; if pregnant women suffering from gestational hypertension, can damage the kidney function, resulting in a large amount of protein from the urine, the blood protein content is reduced, the whole body, including the hands, edema, serious and life-threatening. Therefore, when a pregnant woman has swollen hands, she should consult a doctor as soon as possible to clarify the cause of the disease and under the guidance of a professional physician to avoid delaying the condition and leading to adverse consequences.