Valsartan and hydrochlorothiazide tablets can be taken together, which can increase the effect of lowering blood pressure and reduce the risk of hypokalemia. Valsartan belongs to the angiotensin II receptor antagonist, the main clinical indication is hypertension, long-term oral valsartan patients can appear elevated blood potassium, and some patients may even develop hyperkalemia. Hydrochlorothiazide belongs to the antihypertensive drugs with diuretic effect, and the process of lowering blood pressure will lead to the loss of electrolytes, for example, it can lead to hypokalemia. Valsartan and hydrochlorothiazide are taken at the same time, there is no contraindication to the combination. The antihypertensive effects of the two drugs will be superimposed, resulting in an increased antihypertensive effect, and at the same time the blood potassium will be adjusted to avoid hyperkalemia or hypokalemia. Adverse reactions of valsartan include headache and dizziness, nausea and vomiting, elevated blood potassium, rash, skin itching, etc. It is contraindicated in women who are allergic to the drug components, have severe renal impairment, are pregnant and lactating. Adverse reactions to hydrochlorothiazide include weakness, dizziness, nausea, electrolyte disorders, etc. It is contraindicated in patients who are allergic to the components of the drug. Valsartan and hydrochlorothiazide are both prescription drugs, so you should purchase the drugs from a regular pharmacy or medical institution and choose the drugs under the guidance of a physician.