Patients with enlarged pancreatic head have the following common clinical causes: a. Congenital stenosis at the opening of the duodenal papilla, resulting in obstruction of pancreatic fluid drainage, manifesting as dilated pancreatic ducts and enlarged pancreatic head, which are congenital changes, and may not require special treatment for the time being if there are no obvious clinical symptoms. Second, patients with acute pancreatitis have a large amount of extravasation of pancreatic fluid into the abdominal cavity, causing significant edema and enlargement of the head of the pancreas. The nature of the lesion can be clarified by enhanced CT examination of the pancreas, and anti-infection and rehydration should be given as soon as possible to inhibit the secretion of pancreatic enzymes so that the inflammation of pancreatitis can completely subside and the symptoms of enlarged head of pancreas can be gradually relieved. Third, when the head of the pancreas is accompanied by malignant tumor proliferation, the volume of the head of the pancreas is obviously enlarged, at this time, surgery is needed to remove the tumor cells in the body, and after surgery, chemotherapy and radiotherapy can be combined to achieve certain therapeutic effects.