There are many kinds of common antihypertensive drugs, there is no latest antihypertensive drug, and there is no so-called best antihypertensive drug, you should follow the doctor’s advice to choose the right antihypertensive drug for you. Common antihypertensive drugs include diuretics, calcium antagonists, beta receptor antagonists, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor antagonists (ARBs), and so on. 1. Diuretics: there are thiazides, labeled diuretics and potassium-preserving diuretics. The commonly used ones are hydrochlorothiazide, which is suitable for patients with various degrees of hypertension, simple systolic hypertension or combined diabetes mellitus. Adverse effects include hypokalemia and effects on lipid, glucose, and blood uric acid metabolism. Collapsible diuretics are used in patients with combined renal insufficiency. Potassium-preserving diuretics can cause hyperkalemia, so use with caution in patients with renal insufficiency. 2. β-receptor antagonists: mainly propranolol, applicable to different degrees of hypertension, especially the faster heart rate or chronic heart failure, side effects such as bradycardia, acute heart failure, atrioventricular block is prohibited. 3. Calcium ion antagonist: divided into two categories, non-dihydropyridine class has verapamil, dihydropyridine class is mainly nifedipine. It has no significant effect on lipid and glucose metabolism, so it can be used in patients with diabetes mellitus and coronary artery disease, and the main side effects include accelerated heart rate and facial flushing. 4.ACEI: such as captopril, its slow onset of action, suitable for patients with diabetes and renal target organ damage or hypertension with heart failure, atrial fibrillation, the main side effects are irritating dry cough. 5.ARB: such as valsartan, its therapeutic targets and contraindications are the same as ACEI, generally does not cause irritating dry cough. Please take antihypertensive drugs under the guidance of a specialist.