Severe mitral regurgitation must be operated. If left untreated, it can cause serious complications such as atrial fibrillation and endocardial infection. Severe mitral regurgitation affects normal cardiac blood circulation, resulting in decreased pumping function of the heart and increased cardiac load. It also leads to obstruction of pulmonary venous return and pulmonary venous stasis, resulting in respiratory distress and further development of hypoxia, and finally the formation of pulmonary hypertension and heart failure. If left untreated, it may cause serious complications such as atrial fibrillation. Severe mitral regurgitation is recommended to seek timely medical treatment, surgical treatment under the guidance of the doctor, serious cases can be treated with mitral valve replacement surgery. After surgery, regular follow-up is required. In daily life, avoid strenuous exercise, eat less greasy food, adopt low-salt and low-fat diet, pay more attention to rest, avoid overwork. For patients with severe mitral regurgitation, it is recommended to seek timely medical treatment to avoid more serious consequences.