The side effects of minimally invasive removal of the uterus include premature ovarian failure, decreased sexual function, contact bleeding and vaginal dryness. Removing the uterus through minimally invasive surgery disrupts the dynamic balance of endocrine secretion between the uterus and the ovaries, resulting in premature ovarian failure. Premature ovarian failure significantly reduces the secretion of estrogen in the body, which advances and aggravates the symptoms of menopause. The uterus is not only a reproductive organ, but also an important organ for sexual life. After hysterectomy, the sexual function decreases significantly, which seriously affects the normal sexual life and makes it difficult to achieve orgasm during sex. After hysterectomy, the vaginal stump will appear sub hyperplasia, polyps, etc., and contact bleeding is easy to occur during sex. After hysterectomy, there is no leucorrhoea secreted from the cervix, coupled with the decline in estrogen levels, the vagina becomes dry and dry, and in severe cases, there will be pain during sex.