1. Long-term medication to control symptoms There is no effective drug to cure Parkinson’s, and levodopa is still the “gold standard” for the treatment of Parkinson’s disease. Almost all cases require lifelong medication to control symptoms. The drug treatment plan should be individualized, i.e. the drug should be selected according to the patient’s age, type and severity of symptoms, functional impairment status, expected effects and side effects of the drug given, etc. The treatment plan should also take into account the disease progression in order to use the right drug and add or subtract from the right evidence. 3, the minimum dose, the best effect, that is, “long flow of water, do not seek full effect” almost all anti-Parkinson drugs need to start with a small amount, slowly increase the amount, to achieve individualized dose, to achieve the minimum effective dose to maintain the best effect. The drug treatment of Parkinson’s disease is a complex issue, and levodopa is the most important anti-Parkinsonian drug. In recent years, many adjuvant drugs with different routes of action have been introduced, such as dopaminergic receptor agonists, monoamine oxidase inhibitors, catechol-O-methyltransferase inhibitors, etc. They have their own advantages and disadvantages, and their effects are not ideal when used alone. Therefore, it is important to weigh the advantages and disadvantages of drug therapy for Parkinson’s disease, and to choose the appropriate drugs for better results in combination.