Congenital Heart Disease (CHD) is a group of congenital malformations caused by abnormal development of the heart vessels during fetal life, and its incidence is about 0.7 to 0.8% of live births. There are many types of CHD and the treatment outcome varies, but for most of them, early detection and diagnosis as well as early treatment are crucial. Once medical treatment is delayed, many children die at a young age due to advanced disease, or complications of cardiopulmonary insufficiency, which significantly increases the risk of surgery, or complications of Eisenmenger’s syndrome, which completely eliminates the chance of surgery. In our clinic, we often see parents who regret that they missed the best time to treat their children. In order to facilitate parents’ understanding of how to detect congenital heart disease in infants at an early stage so that they can seek timely diagnosis and treatment, the common symptoms of congenital heart disease are described as follows for your knowledge: 1. shortness of breath: during the newborn or infant period, the child is found to be weak in sucking when eating milk, shallow breathing, stopping after a few sips, feeling tired and sweating profusely. Some children have nodding breathing or a depression in the upper sternal fossa during inspiration. 2, repeated respiratory infections or pneumonia: this is the most common symptom of left-to-right shunt type precordial disease, because the lungs are congested, a mild respiratory infection can easily cause bronchopneumonia, and parents may feel that the child is prone to morbidity and low resistance. 3, hoarseness: Some children with precocious heart disease show a strong cry at birth, but as the months grow older, the cry gradually becomes faint and even hoarse. 4, growth retardation: precardiac disease in some infants and young children show no weight gain, which is due to insufficient blood flow and blood oxygen supply in the body circulation, growth and development is delayed than the same age children, their weight lag more obvious. 5, heart murmur: physical examination or due to respiratory infection auscultation found heart murmur, must be consulted as soon as possible to further clarify the diagnosis, of course, there is a heart murmur is not all precordial disease. 6, “chicken chest”: Some children have an enlarged heart that makes the sternum rise up and look like a chicken chest, but they are in fact patients with severe precardiac disease, and clinically many of these children are misdiagnosed as chicken chest, resulting in delayed treatment. 7, cyanosis or cyanosis: left-to-right shunt type of precordial disease usually does not appear cyanosis, but if not treated in time, causing complications of pulmonary hypertension, cyanosis can appear. However, most of the children with right-to-left shunt preconditioning have cyanosis, and the cyanosis of the lips and nail bed is more obvious, especially after crying and activity. If cyanosis appears in the neonatal period, the preconditioning may be complete transposition of the great arteries, pulmonary atresia, etc.; cyanosis in tetralogy of Fallot mostly appears around 3 months after birth. 8. Squatting phenomenon: Patients with cyanotic preconditioning, especially in Farrow’s tetralogy of Fallot, often have the phenomenon of squatting after activity, which is manifested by automatically adopting a squatting position or taking a chest and knee position after walking for a certain distance, and then standing up again after a moment of rest. Squatting process can make the hypoxic condition improved. 9, pestle-like fingers (toes): due to long-term hypoxia, the child’s fingers (toes) end of the soft tissue abnormal hyperplasia, so that the fingers, toes are drumstick-like changes, in the cyanotic precocious tetralogy of Fallot children often appear. 10, fainting: also known as hypoxic seizures, often occurring during breastfeeding, crying, defecation, due to severe hypoxia so that the child sudden respiratory distress, cyanosis aggravated, loss of consciousness and even convulsions. 11. Hemoptysis: In patients with cyanotic preconditioning, the rupture of the blood vessels forming the collateral circulation in the lungs can cause hemoptysis due to prolonged hypoxia. If parents find their babies have one or more of the above symptoms, they should bring their children to the hospital as soon as possible to avoid delaying treatment and missing the best time for treatment.