In general, the severity of epilepsy is related to its ability to be controlled. The frequency of seizures and the duration of each seizure, and the presence or absence of convulsions are important indicators to assess the severity of epilepsy. However, as a chronic brain disease, patients with epilepsy also suffer from co-morbidities such as emotional instability, sleep disturbances, memory loss, and side effects of long-term antiepileptic medications. A large Canadian clinical study in 2015 showed that one year of seizure-free epilepsy, the number of antiepileptic drugs used, side effects of medications, co-occurring depression and anxiety, and seizure-related disability were all important indicators of the severity of the patient’s self-perceived condition.