Whether metatarsalgia can be cured by itself depends on the situation and cannot be generalized.1. If metatarsalgia is caused by periostitis, synovitis, arthritis, and the condition is not serious, most of them can be cured by themselves after some basic physical therapy or rest.2. However, if metatarsalgia is caused by infections, rheumatoid disorders, or mandatory spondylitis, which are caused by aseptic inflammation, it is difficult to be cured by yourself. However, if the metatarsalgia is caused by infection, rheumatoid disease, compulsory spondylitis, these aseptic inflammation, it is very difficult to heal by oneself, and need to be treated, including non-steroidal anti-inflammatory drugs, blood circulation and blood stasis medicines, topical creams and physical therapy.3. If the metatarsalgia is pathologically related, such as a localized tumor, it can’t be healed on its own, and needs to be surgically removed and fixed by implantation.