Patients with gout usually have no obvious symptoms in the early stages, and some of them will have persistent hyperuricemia. The etiology and pathogenesis of gout have not yet been clarified, and most of them are caused by hyperuricemia. Gout patients in the early stage of no obvious clinical manifestations, the patient only persistent hyperuricemia, but the patient has not yet occurred arthritis, gout stone or uric acid stone phenomenon. Patients with gout have no specific symptoms in the early stages, but as the patient’s condition progresses, joint pain, swelling, gout stone formation, joint deformity, etc. may occur. In addition, patients may also have proteinuria, hematuria, kidney function abnormalities and other manifestations. It is recommended that patients with persistent hyperuricemia should consult a doctor in time to find out the cause and standardize the diagnosis and treatment under the doctor’s guidance.