Duloxetine is a psychotropic medication that is primarily used to treat depression as well as generalized anxiety disorder, and can also be used to treat chronic musculoskeletal pain. Adverse reactions to this product include nausea, dry mouth, constipation, diarrhea, vomiting, loss of appetite, dizziness, drowsiness, and tremor. This medication should not be stopped abruptly, but needs to be slowly tapered to discontinuation, otherwise dizziness, headache, nausea, vomiting, insomnia anxiety and other discomforts may occur. It should also be noted that patients with hepatic insufficiency, mainly chronic liver disease as well as cirrhosis, cannot use this drug. Duloxetine is also not recommended for patients with renal function if creatinine clearance is <30ml/min. The use of Duloxetine must follow the instructions of the psychiatrist, do not use or stop the drug on your own, otherwise it is likely to cause serious adverse consequences.