Interventional closure of patent foramen ovale is a cardiac surgical procedure to repair the atrial septum. Foramen ovale is a congenital structural abnormality of the heart, which is usually a developmental abnormality caused by the failure of the foramen ovale to close over the right and left atrial septum in infants within the first year of life. Some children require interventional closure of the foramen ovale. The procedure involves puncturing the femoral vein at the base of the thigh, following the vessel into the right atrium, and then reaching the foramen ovale to release the blocking device. Most children with patent foramen ovale do not have symptoms, but some may have abnormal right-to-left blood flow when the left atrium pressure is lower than the right atrium, resulting in symptoms such as paradoxical embolism, which should be treated aggressively. For interventional blockage of patent foramen ovale, it is important to choose a regular hospital and take good care of the patient after the surgery.