Patients with chronic kidney disease often suffer from renal anemia, once renal anemia occurs, it should be actively treated as follows: First, recombinant human erythropoietin treatment can be carried out, and the commonly used drugs in the clinic include Rohypnol or Epidio, etc.; Second, active supplementation of iron (polysaccharide-iron complexes) as well as folic acid for the supplementation of raw materials for hematopoiesis, so as to correct the anemia; Third, patients with chronic kidney disease and uremia need early maintenance dialysis; Fourth, patients with hematocrit below 60g/L need timely blood transfusion therapy. Early maintenance dialysis is needed; Fourth, patients with hematocrit less than 60g/L need timely blood transfusion treatment. In addition, it should also correct the patient’s acidosis and treat hyperparathyroidism, through these comprehensive treatment to improve renal anemia.