Left buttock pain to the calf may be lower limb muscle strain, lumbar spine disease and pear-shaped muscle syndrome and other causes, need to be on the cause of the general treatment, drug treatment, surgical treatment. 1. Lower limb muscle strain: for lower limb muscle strain, the soreness symptoms can be reduced when resting; can follow the doctor’s prescription oral celecoxib and other painkillers, ethylphenidate hydrochloride tablets and other muscle relaxants; the conservative treatment is ineffective, the feasibility of minimally invasive surgery. 2. Lumbar spine disease: for lumbar spine disease such as lumbar disc herniation and lumbar spondylolisthesis caused by sciatic nerve compression caused by the left buttock pain to the calf, bed rest. Oral ibuprofen and other non-steroidal anti-inflammatory drugs, prednisone and other glucocorticoids can help relieve pain symptoms. If the condition is serious, minimally invasive surgery can be performed to remove the nucleus pulposus to relieve nerve compression. 3. Piriformis syndrome: Piriformis syndrome can be caused by inflammation, edema and adhesion of the piriformis muscle, which compresses the sciatic nerve, and the treatment requires conservative treatment such as physiotherapy and hot compresses. Oral non-steroidal anti-inflammatory drugs such as celecoxib can also be taken. If the condition is not relieved, surgery can be considered to loosen the adhesions. It is recommended that people with left buttock pain to the calf go to the regular hospital in time, to clarify the cause of the disease, under the guidance of the doctor to carry out standardized treatment, so as to avoid delaying the condition.