Prednisone acetate is a glucocorticoid, which can cause a person to gain weight if taken in large doses for a long time. In order to avoid this side effect, the following aspects should be noted: First, the diet should be controlled as much as possible, especially the pasta containing starch, and usually eat more vegetables and fruits rich in vitamins. Second, the intake of sugar and salt must be reduced as much as possible, especially cakes and other temporary should be avoided. Third, you can use more diuretic vegetables, especially winter melon, can effectively prevent glucocorticoid-induced obesity. Fourth, some milk products, especially pure milk, are rich in calcium and protein, which can effectively prevent the side effects of glucocorticoids such as osteoporosis.