One leg can’t feel hot or cold, which is clinically known as superficial sensory loss, in the active treatment of the primary disease, but also need to use functional rehabilitation exercises to help recovery. A leg can not feel hot and cold because of various reasons lead to sensory afferent nerves, the posterior horn, the spinal cord thalamus lateral tract and other superficial sensory pathway damage, such as spinal cord trauma, spinal cord cavernous syndrome, spinal cord tumors, cerebral vascular disease, resulting in patients with pain and temperature sensory loss at the same time. 1. Cerebrovascular disease: if cerebral hemorrhage, give mannitol and other cranial pressure lowering treatment, and at the same time can give cytarabine and other drugs to promote brain cell metabolism symptomatic treatment, to promote functional recovery. If cerebral infarction, intravenous thrombolytic therapy such as alteplase should be given in time to restore cerebral blood flow and promote the recovery of brain function. 2. Spinal cord injury: trauma, tumor and spinal cord cavity will affect the sensory function of the lower limbs and should be treated surgically. After the cause of treatment is stabilized, we should actively seek professional rehabilitation doctors to carry out functional rehabilitation exercises, such as baking electricity, acupuncture, massage, physical factor therapy, mechanical assisted movement of the affected limbs, etc., to carry out regular and periodic gradual rehabilitation exercises, so as to maximize the restoration of the sensation and function of the affected limbs. If you can’t feel hot or cold in one leg, you need to consult a doctor in time and standardize the treatment to avoid delaying the condition.