The causes of reduced glomerular filtration rate are generally primary and secondary kidney diseases. Primary renal diseases mainly include acute glomerulonephritis, chronic glomerulonephritis, acute interstitial nephritis, chronic interstitial nephritis, and acute progressive glomerulonephritis, etc. Secondary renal diseases mainly include diabetic nephropathy, lupus nephritis, hepatitis B-related nephropathy, hypertensive nephropathy, myeloma nephropathy, and renal amyloidosis, etc. Therefore, if reduced glomerular filtration rate is found, it is recommended to visit a regular hospital, where you can improve blood routine, blood biochemistry, 24-hour UP quantification, urine Ben-Zhou protein, coagulation system, urological ultrasound and other related tests to clearly diagnose the disease and give active treatment.