The uncomfortable pressing feeling in the left chest may be due to physiological factors, coronary heart disease, heart failure, pericarditis, pneumothorax, etc., which need to be treated with medication or surgery for the cause. 1. Physiological factors such as lack of rest, excessive stress, nervousness and anxiety, and overwork: may cause this symptom, moderate rest, and keep your mood happy. 2. Coronary heart disease: coronary artery atherosclerotic plaque, coronary artery spasm, coronary artery embolism and other factors lead to myocardial blood supply limitation, myocardial ischemia and cause angina pectoris, so this symptom. You can take aspirin, clopidogrel, atorvastatin, isosorbide nitrate and other medications, or through interventional surgery, cardiac bypass surgery and other treatments. 3. Heart failure: Ventricular ejection dysfunction, resulting in circulatory stasis, so the symptoms will appear. It can be treated with drugs such as sodium nitroprusside, digoxin, furosemide, spironolactone, sacubitril valsartan and so on. 4. Pericarditis: Inflammatory exudation occurs after pericardial infection, leading to pericardial effusion, which compresses the heart and causes this symptom. It can be treated with aspirin, colchicine, levofloxacin, prednisone and other drugs or pericardiocentesis. 5. Pneumothorax: trauma and other factors lead to localized breakage on the surface of the left chest wall or the surface of the left lung, and outside gas enters into the pleural cavity under the effect of atmospheric pressure, increasing the pressure in the pleural cavity and the symptom appears. You can use morphine, pethidine and other drugs for analgesia, and treat it by chest puncture aspiration, closed chest drainage and so on. Pay attention to the use of drugs under the guidance of physicians. Left chest discomfort pressure should be timely to the hospital, under the guidance of the doctor to identify the causes and be targeted treatment.