Polycystic ovary syndrome mainly addresses ovulation problems

  Polycystic ovarian syndrome (PCOS) is an endocrine disorder in which reproductive dysfunction coexists with abnormal glucose metabolism. It mainly affects young women, and according to statistics, 6-10% of women worldwide suffer from polycystic ovarian syndrome.  Most infertility specialists or fertility center doctors believe that polycystic ovary syndrome is a complex disease, with different clinical manifestations in different patients. Endometrial cancer and infertility.  (1) The etiology of polycystic ovary syndrome is currently unknown. Due to the complexity and high heterogeneity of its clinical manifestations, research on the etiology of polycystic ovary syndrome is the focus of study by clinicians in infertility hospitals, and is a hot spot and difficult research area for many gynecologists and reproductive endocrinologists. At present, it is generally accepted that polycystic ovary syndrome is a polygenic genetic disease with a combination of genetic and environmental factors. The possible causative factors are broadly summarized as follows: follicular dysgenesis, abnormal ovarian sex hormone synthesis, hyperinsulinemia, genetic factors and environmental factors.  (2) Lack of menstruation and ovulation is a warning for polycystic ovary syndrome. The typical clinical manifestations of polycystic ovary syndrome are lack of menstruation, polycystic ovarian changes and lack of ovulation. Sporadic menstruation often indicates that the body is not ovulating, often less than 10 times a year.  Short sporadic periods are not harmful in themselves, but they are often due to ovarian failure to ovulate, so patients with polycystic ovary syndrome tend to have infertility problems, which does not mean that polycystic ovaries are necessarily infertile, but the chance of infertility is relatively high.  With anovulatory menstrual cycles, there is a lack of production of corpus luteum and a relative lack of progesterone. Progesterone is protective for the endometrium. If the endometrium is stimulated by estrogen for a long time, it is prone to endometrial monoproliferative changes and even cancer, so endometrial cancer is also a long-term risk for patients with polycystic ovary syndrome.  (3) Polycystic ovary syndrome is not absolute infertility Although polycystic ovary syndrome can lead to infertility, it is not absolute, and there are a few patients who occasionally ovulate on their own, also known as sporadic ovulation. Although it is a rare and seemingly “extravagant” egg, as long as the egg is ovulated, there is a possibility of pregnancy, and although the probability is small, it is not 100% infertility.  (4) The diagnosis of polycystic ovary syndrome can be determined by meeting two criteria The early diagnostic criteria of polycystic ovary syndrome are not uniform. The diagnosis of PCOS can be confirmed if any 2 of the following items are met: (1) sporadic ovulation and/or anovulation; (2) clinical manifestations and/or biochemical changes of hyperandrogenemia; (3) polycystic ovaries (≥12 follicles of 2-9 mm in diameter and/or ovarian volume ≥10 ml in one or both ovaries) are detected on ultrasonography.  (5) Health management is particularly important in patients with polycystic ovary syndrome According to the latest research in reproductive health and infertility industry, weight loss of 5%-10% in patients with polycystic ovary syndrome can help improve insulin resistance and ovulation status.  Patients can use weight loss, dietary therapy, active exercise, and good mood as adjunctive treatment in addition to medication and surgery for patients with polycystic ovary syndrome.