Headache in gastroenteritis may be the result of severe systemic toxic symptoms complicated by intracranial infection, and pain caused by pulling on the meninges. Gastroenteritis is an acute inflammation of the gastrointestinal mucosa, usually manifested as nausea, vomiting, abdominal pain, diarrhea. In severe cases, there is persistent high fever, dehydration, electrolyte disorders, and shock. Vomiting is common in children and diarrhea is common in adults. Headache, general malaise, and varying degrees of toxicity may also occur. Gastroenteritis usually occurs in the summer and fall, because in the summer is hotter, the chance of food spoilage will be higher, the food is more intolerant of storage than in the winter, so it is likely to eat contaminated food and cause acute gastroenteritis. Acute gastroenteritis, if particularly severe and unchecked, is likely to lead to organ failure, and even complicate intracranial infections and pain caused by pulling on the meninges. Therefore, when gastroenteritis occurs and causes headaches, it is necessary to seek medical treatment in time to avoid delaying the condition.