Biliary atresia is a group of unexplained occlusive lesions of the intrahepatic and extrahepatic bile ducts, with biliary stasis leading to progressive hepatic fibrosis and eventually cirrhosis and endangering the life of the child. Biliary atresia (BA) is generally referred to as congenital biliary atresia, which is common in infancy, and is a very serious disease of the hepatobiliary system, characterized by progressive inflammation/fibrosis of the intra/extrahepatic bile ducts. In untreated children, complications such as biliary cirrhosis, portal hypertension, and liver failure can occur in later stages. However, early diagnosis is difficult and surgical treatment is unsatisfactory. Common clinical manifestations are delayed resolution of jaundice after birth (full-term infants>2 weeks/preterm infants>3 weeks), or reappearance of jaundice after its resolution, which continues to worsen. The color of the stool gradually changes to terra cotta, and the color of the urine gradually deepens to a strong tea color. The disease can be diagnosed by blood laboratory tests, ultrasound, MRI of the pancreaticobiliary duct, endoscopic retrograde cholangiopancreatography, and biopsy of liver tissue. If biliary atresia is considered, the family should bring the child to the doctor in time to complete the relevant examinations, make a clear diagnosis, and then take the appropriate treatment plan.