Bile reflux can be caused either by a problem with the stomach or because of a biliary tract disorder. Symptomatic treatment is needed according to the cause. 1. Gastrointestinal diseases: bile reflux is mainly related to poor gastric motility, gastric contents can not be emptied in time, which further promotes the secretion of bile and also causes bile reflux, which can cause bile reflux gastritis. This situation can be treated with gastric mucosal protectants such as magnesium aluminum carbonate, or gastric stimulants such as domperidone. 2. Biliary tract diseases: patients with chronic cholecystitis can suffer from bile reflux due to the thickening of the gallbladder wall, the decrease of bile concentration function, the limited storage of bile, and the large amount of bile discharged into the intestine. Therefore, for patients with recurrent cholecystitis with bile reflux, cholecystectomy can be performed. In conclusion, after the appearance of bile reflux, should promptly go to the regular hospital, under the guidance of the doctor for treatment.