Infectious skin damage in the acute phase of AIDS manifests itself as infection by various pathogenic microorganisms, but the condition is more serious than that of the average patient, such as herpes zoster, herpes simplex, warts, fungal infections, bacterial infections and so on. 1. Herpes zoster: the scope of involvement is often large, blisters, blisters, blood blisters can appear, pain is intense, very easy to secondary bacterial infection, can cause encephalitis, pneumonia, and even death. 2. Herpes simplex: frequent recurrence, the distribution of lesions is limited or disseminated, manifested as persistent oral, genital, perianal severe herpes, can be long-term and the formation of deep ulcers. 3. Warts: can be manifested as common warts, flat warts, infectious molluscum contagiosum, male homosexual patients perianal, rectal often have warts. 4. Fungal infections: thrush is the earliest symptom of immunodeficiency, in addition to more serious superficial fungal infections (such as tinea versicolor, tinea cruris and tinea versicolor, etc.), sometimes atypical manifestations, need to do fungal microscopy and culture; 10% to 13% of patients with AIDS can occur cryptococcal infections, often manifested as herpes-like lesions, the central nervous system is easily involved. 5. Bacterial infection: manifested as folliculitis, multiple skin abscesses or boils. AIDS rash does not have any specificity and is very similar to the rash symptoms caused by other viral infections, so it cannot be used as a diagnosis of AIDS. After the occurrence of high-risk contacts, even if the appearance of a similar rash manifestations, but also can not self judgment has been infected, want to determine whether the organism is infected with HIV, must rely on the results of the laboratory HIV-specific test.