Take valsartan or irbesartan.

Valsartan and Irbesartan, as selective angiotensin II receptor antagonists, can be used in patients with hypertension to take, and there is no significant difference in lowering blood pressure.
There is also no significant difference between valsartan and irbesartan in terms of damage to target organ damage, which protects the function of target organ function, such as heart, brain, kidney and other organ damage. The choice of antihypertensive drugs is based on the level of blood pressure and the type of target organ damage.
Valsartan can comprehensively protect target organs from damage in patients with cardiovascular disease, while Irbesartan can be more effective in patients with renal insufficiency to bring down urinary proteins, among others.
For high blood pressure levels of grade 2 or higher, it is recommended to start treatment with two or more different antihypertensive medications, one being a sartan and a diphenhydramine, and the other being a combination of a sartan and a diuretic.