Uremia, also known as renal failure, with abnormalities in water and salt metabolism, hormone metabolism and electrolyte metabolism, and active substance metabolism, will have some characteristic facial changes. The first thing to see should be anemia appearance, because uremia after uremia erythropoietin reduction will cause anemia, see the patient should be anemia appearance. The uremic patient’s sweat gland secretion will be reduced abnormally, and the skin will appear dry, sometimes there will be crumbly, scaly peeling manifestation. Because of the abnormal hormone levels, uremia may lose its luster, there is no moist feeling, and part of the pigmentation, there may be itching sensation, and the hair is dry. Because of the effect on water and salt metabolism, patients with uremia may sometimes also have this manifestation of swelling and high blood pressure.