Fasting hiccups may be caused by gastric acid stimulation, gastrointestinal neurosis and some gastrointestinal diseases in the fasting state. 1. If the stomach acid secretion in fasting state is too much, it will stimulate the gastrointestinal mucosa to cause hiccups, this situation usually just need to eat some food can be relieved, do not need to carry out special treatment. 2. Gastrointestinal neurosis: in patients with gastrointestinal neurosis, gastrointestinal peristalsis is weakened, causing diaphragmatic spasm and hiccups. You can use psychoactive drugs and intestinal probiotics to regulate the microenvironment of the gastrointestinal tract under the guidance of a doctor, and you can also receive professional consultation and treatment from a psychiatrist. 3. If there are gastrointestinal diseases such as chronic gastritis, gastric ulcer and other diseases. It can also lead to hiccups on an empty stomach, and a gastroscopy can clarify the presence or absence of lesions. Fasting hiccups may also be related to emotions, reflux esophagitis, etc. If frequent hiccups occur, it is recommended to go to the gastroenterology department of the hospital for examination, and take appropriate treatment after clarifying the disease.